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25x: Biology, Fifth Edition - Part 1

A full-color biology workbook with complete lessons and structured science practice.

★★★★★ 5.0 · 12 reviews
Science High School Academic
  • 527 pages
  • 6 units
  • 14 pages to preview
  • Published by 3andB

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What you get

  • Twenty-five complete biology lessons spanning foundations of life through ecology.
  • All-new articles, instructional images, and updated hypotheticals.
  • Redesigned reflection questions for discussion and real-world application.
  • Full-color, 527-page student workbook from 3andB.

For high school students in an academic science program studying biology topics.

About this workbook

25x: Biology, Fifth Edition - Part 1 is a 527-page, full-color student workbook from 3andB with 25 complete biology lessons. Rebuilt for the Fifth Edition, it includes all-new articles, instructional images, updated hypotheticals, redesigned reflection questions, and fewer, more meaningful prompts for discussion and real-world application.

Lessons cover foundations of life, cells, metabolism, molecular biology, evolution, and ecology. Each includes guided notes, vocabulary practice, an IV/DV/Hypothesis Activity, a Data Analysis Activity, a crossword, a word search, and access to a ready-to-use online slide deck.

The workbook aligns with Next Generation Science Standards and Texas TEKS and does not include answer keys. Students build practice identifying variables, developing testable hypotheses, interpreting evidence, recognizing patterns, and drawing conclusions.

The same shape, every time

In every lesson

A teacher can hand out any lesson in this book and know exactly what a student is getting.

  1. 1Guided notes
  2. 2Vocabulary practice
  3. 3IV/DV/Hypothesis Activity
  4. 4Data Analysis Activity
  5. 5Crossword
  6. 6Word search
  7. 7Ready-to-use online slide deck access

What's inside

6 units, start to finish.

  • X. What Is Biology?
Unit 1: Foundations of Life and Cell Structure
  • Lesson 1: Characteristics of Life — HS-LS1-2
  • Lesson 2: Water and Macromolecules — HS-LS1-6
  • Lesson 3: Enzymes — HS-LS1-1
Unit 2: Cell Structure and Function
  • Lesson 4: Cell Theory and Types of Cells — HS-LS1-2
  • Lesson 5: Cell Organelles and Functions — HS-LS1-2
  • Lesson 6: Cell Cycle — HS-LS1-4
Unit 3: Energy and Metabolism
  • Lesson 7: Photosynthesis — HS-LS1-5
  • Lesson 8: Cellular Respiration — HS-LS1-7
  • Lesson 9: Aerobic and Anaerobic Respiration — HS-LS1-7
  • Lesson 10: Fermentation — HS-LS1-7
Unit 4: Molecular Biology and Gene Expression
  • Lesson 11: Structure and Function of DNA and RNA — HS-LS1-1
  • Lesson 12: DNA Replication — HS-LS1-1
  • Lesson 13: Protein Synthesis — HS-LS1-1
  • Lesson 14: Meiosis — HS-LS1-4
  • Lesson 15: Inheritance — HS-LS3-1
  • Lesson 16: Mendelian Genetics — HS-LS3-2
  • Lesson 17: Mutations — HS-LS3-2
Unit 5: Evolution
  • Lesson 18: Evolution and Natural Selection — HS-LS4-2
  • Lesson 19: Population Genetics — HS-LS4-3
  • Lesson 20: Mechanisms of Evolution — HS-LS4-4
Unit 6: Ecology
  • Lesson 21: Ecology and Energy Flow — HS-LS2-3
  • Lesson 22: Population Ecology — HS-LS2-1
  • Lesson 23: Biogeochemical Cycles — HS-LS2-3
  • Lesson 24: Symbiosis and Species Interactions — HS-LS2-8
  • Lesson 25: Ecological Succession — HS-LS2-7

From teachers who bought it

What teachers say

★★★★★ 5.0 out of 5 · 12 reviews

Wonderful book

A good Biology book that will make teaching this course a lot easier for me.
MBS Verified TPT purchase
Myself and my students love this resource! It's great
VF Verified TPT purchase

Well written articles that keeps students interests.

I have been looking for short reading articles to add to my current curriculum, and these are great, engaging resources on biology topics that engage students.
MD Verified TPT purchase

A Teacher’s Dream Biology Workbook

Finally—a biology curriculum that actually teaches! This 25-lesson workbook is packed with everything teachers need to make complex topics clear and engaging. The new 2025–26 updates are incredible: deeper articles, more relevant hypotheticals, and ready-to-use slide decks that save hours of prep time. I love how every lesson connects science to real life, encouraging students to think critically and reflect personally. The guided notes, vocabulary, and answer keys make it easy to teach, grade, and keep students engaged. It’s hands down one of the most complete and thoughtful biology workbooks I’ve seen.
DDCS Verified Amazon purchase

Useful!

This was worth every dollar. It's packed knowledge and heaps of content. The lessons were really clear and easy to follow which is something that anyone will appreciate. I also want to highlight the activities designed to keep you engaged. Bravo!
P Verified Amazon purchase

Biology

An awesome supplemental curriculum for any student interested in the health care field. This book is filled with comprehensive information and worksheets to complete. Great for homeschooling!
GM Verified Amazon purchase

Useful and playful guide

I got this book to help a friend, who struggles with Biology, and I read it too. I liked that this book is playful, it has crossword puzzles and word searches too, to relax you while reinforcing learning. The guided notes and the reflecting questions are very useful too.
CB Verified Amazon purchase

Biology textbook

This is a great biology book. It is designed to make teaching and learning biology engaging and practical. The book covers various topics, and includes 25 complete lessons with articles, guided notes, vocabulary, reflection questions, hypotheticals, puzzles, and reinforcement activities. Each lesson connects core biology concepts like cell structure, genetics, evolution, and ecology to real-life applications and student experiences.
R Verified Amazon purchase

Great Book

This book makes biology concepts easy to understand and engaging for both middle and high school students. The explanations are straightforward, and the examples make even complex topics approachable. It’s an excellent resource for study, review, or reinforcing classroom lessons. A valuable tool for students and teachers alike.
J Verified Amazon purchase

Their updated 25x Biology is a strong resource for high school biology classrooms and home schools.

Their updated 25x Biology is a strong resource for high school biology classrooms and home schools. Each lesson is now much more comprehensive and provides greater depth. Objectives, top 5 most important facts, 3 page article, guided notes, hypotheticals, and reflection questions - then vocab, crossword, and word search - make each lesson comprehensive, engaging, and fun. They also provide really good slide decks on their website for every lessons.
DH Verified Amazon purchase

Never too late to learn

I loved to be able to brush up on a few things throughout this book. It was a learning experience that was made into a game with my family. Working on the medical field with inquisitive children is a plus. Things forgotten were brought back up here and that’s a major help.
L Verified Amazon purchase

Great Supplemental Lessons

These lessons have been for introducing or reviewing concepts. They're laid out pretty well, so they also been useful for sub days.
LH Verified TPT purchase

Sample pages

14 pages photographed from the book — open any one full size.

Written against

Standards this workbook covers

Questions teachers ask

What biology topics does this workbook cover?

Lessons cover foundations of life, cells, metabolism, molecular biology, evolution, and ecology.

Does this workbook include answer keys?

No, the workbook does not include answer keys.

What skills do students practice?

Students practice identifying variables, developing testable hypotheses, interpreting evidence, recognizing patterns, and drawing conclusions.

How many pages is the workbook?

The workbook is 527 pages.

Ready for your classroom

25x: Biology, Fifth Edition - Part 1 · 527 pages · High School

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