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25x: Life Sciences - MS - Fifth Edition

A complete middle school life science course pairs consistent lessons with answer keys and teacher lecture notes.

★★★★★ 5.0 · 12 reviews
Science Middle School Academic
  • 371 pages
  • 5 units
  • 12 pages to preview
  • Published by 3andB

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What you get

  • Complete answer keys and teacher lecture notes keep instructional support together in one volume.
  • Five connected units organize 25 lessons from biology foundations through ecology and ecosystems.
  • Updated photographs and diagrams make life science content more visual across the course.
  • Expanded data-analysis opportunities give students repeated practice interpreting evidence and defending their thinking.
  • Consistent lesson structure supports independent study, supplemental science, and intervention settings.
  • Real-world applications help students connect scientific concepts and apply biological principles to new situations.

Designed for middle school classrooms, homeschool programs, independent study, supplemental science, and intervention. The full edition also supports teachers, homeschool educators, tutors, and other instructors.

About this workbook

25x: Life Sciences - MS - Fifth Edition is a 371-page black-and-white middle school life science workbook from 3andB, with complete answer keys and teacher lecture notes. Across 25 lessons in five connected units, the course covers foundations of biology, human body systems, cell division and genetics, evolution and adaptation, and ecology and ecosystems.

Lessons combine accessible science reading, guided notes, vocabulary, reflection questions, data analysis, hypothetical situations, crosswords, word searches, and real-world application. It is designed for middle school classrooms, homeschool programs, independent study, supplemental science, and intervention.

The workbook aligns with NGSS Middle School Life Science and Texas TEKS Science for Grades 6–8. Students investigate living systems, interpret data, apply biological principles, evaluate evidence, and draw supported conclusions.

The same shape, every time

In every lesson

A teacher can hand out any lesson in this book and know exactly what a student is getting.

  1. 1Accessible science reading
  2. 2Guided notes
  3. 3Reflection questions
  4. 4Data analysis
  5. 5Hypothetical situations
  6. 6Vocabulary
  7. 7Crosswords and word searches
  8. 8Real-world application

What's inside

5 units, start to finish.

Unit 1: Life’s Building Blocks 🔬
  • Characteristics of Living Things
  • Classification of Living Things
  • Cells
  • Cell Parts
  • Photosynthesis & Aerobic Respiration
Unit 2: Human Body Systems 💓
  • 6. Human Body Systems
  • 7. The Digestive System
  • 8. The Respiratory System
  • 9. The Circulatory System
  • 10. The Skeletal & Muscular Systems
Unit 3: Genetics & Heredity 🧠
  • 11. Cell Division: Mitosis
  • 12. Meiosis & Reproduction
  • 13. DNA Structure & Function
  • 14. Genetics & Heredity
  • 15. The Nervous System
Unit 4: Evolution & Adaptation 🌍
  • 16. Introduction to Evolution
  • 17. Natural Selection
  • 18. Adaptations & Survival
  • 19. Fossils & The Fossil Record
  • 20. Biodiversity & Conservation
Unit 5: Ecology & Interdependence 🌱
  • 21. Ecology & Levels of Organization
  • 22. Autotrophs & Heterotrophs
  • 23. Food Chains & Food Webs
  • 24. Symbiosis & Ecosystem Interactions
  • 25. Ecosystems & Biomes

From teachers who bought it

What teachers say

★★★★★ 5.0 out of 5 · 12 reviews

Fantastic bundle of books

These books are great and terrific for helping me teach these science courses to my students!
MBS Verified TPT purchase

Life-science workbook

This bundle is an absolute goldmine for my 7th grade science classes! It covers exactly what I need and provides incredible structure and depth. The materials are clear, organized, and packed with rigorous content and engaging activities that make complex topics accessible for my students. It's been saving me hours of lesson prep. Worth every single penny!
EO Verified TPT purchase

Supplemental curriculum

I use this in my special education program as a supplemental material that the kids are actually engaged in.
S Verified Amazon purchase
Myself and my students love this resource! It's great
V Verified TPT purchase

Great workbook for a year of middle school biology

As a high school science teacher, I enjoyed reading this middle school biology workbook. I was happy to see that the NGSS standards were covered in a traditional manner. There were some engaging pictures of animals and other things that kids might like as well as puzzles. I liked that the book was divided into 5 units, to go along with the NGSS standards, and that each one was covered with the same format. The key at the end described activities for each unit, listing mostly easily obtainable low-cost materials. The key included everything including critical thinking exercises but did not cover discussion of the chapter hypotheticals. Therefore I would love to see a companion workbook with materials lists by chapter, data sheets and relevant lab worksheets, and discussion of the hypotheticals. Also, I might suggest to interested entrepreneurial individuals that they might consider marketing materials kits to go with the activities.
ST Verified Amazon purchase

A Well-Crafted, High Value Resource

The curriculum my school provided was incomplete, and the 25x resources were the perfect addition to providing a higher value of education to my students. The content is high quality and the questions are well-written. I could see how using all the resources would create a consistent education for students, but the similar format may eventually become repetitive. I do plan on holding on to these resources for years to come.
RA Verified TPT purchase

Well organized resource!

I used this to review my students before state testing! It was a great resource! I think next year I will use this to introduce my students to new topics or to reinforce my teaching.
CAWMB Verified TPT purchase

Great Resource

Very engaging for students. They look forward to reading and interacting with this resource!
SK Verified TPT purchase

Exactly what middle school science should be—clear, engaging, and packed with value

I picked up 25x: Life Sciences to help support middle school learning at home, and I’m genuinely impressed with how well this workbook is put together. The layout is clean, the explanations are easy to follow, and every chapter builds in a way that actually keeps students interested. The guided notes, crosswords, “What if?” scenarios, and reflection questions make the lessons feel interactive instead of dry. I especially appreciate the answer keys, online intro videos, and lecture-style notes—it feels like having a full teacher’s toolkit in one place. This book covers everything: cells, genetics, body systems, evolution, ecology, and more, all in a way that makes sense for middle school students. It’s one of the most complete and accessible science resources I’ve seen, and I’m glad I bought it. Highly recommended for parents, teachers, and homeschoolers who want a solid, well-structured life science curriculum.
JB Verified Amazon purchase
Really good supplemental material with this bundle. It has really good material to hopefully drive home the concepts.
TD Verified TPT purchase

Middle schoolers dream science lesson, quick & easy

This book keeps life science topics simple and easy to understand. I liked how each mini-lesson focused on one clear idea, like ecosystems or genetics, without overloading with details. The short quizzes after each section were helpful for checking understanding. Great for middle schoolers who need quick, focused lessons.
DL Verified Amazon purchase
My students did well with this. They worked on finding the answers in the source and reviewing key information.
SM Verified TPT purchase

Sample pages

12 pages photographed from the book — open any one full size.

Written against

Standards this workbook covers

Questions teachers ask

Does the workbook include answer keys?

Yes, this full workbook edition includes complete answer keys and teacher lecture notes. These instructional materials are provided with the entire course in one volume.

What topics does the workbook cover?

The course covers foundations of biology, human body systems, cell division and genetics, evolution and adaptation, and ecology and ecosystems. Topics range from cells, DNA, and heredity to natural selection, biodiversity, food webs, and biomes.

What is new in the Fifth Edition?

The Fifth Edition includes new and updated content, substantially more photographs and diagrams, and additional questions. It also expands data-analysis opportunities and critical thinking throughout the course.

What will students practice in this course?

Students investigate living systems, examine evidence, interpret data, explore relationships, and apply biological principles. They also evaluate evidence, connect concepts to the living world, and draw supported conclusions.

Can I preview the workbook?

Yes, this page provides a chapter preview, the chapter answer key, and a video. Free materials also include the student workbook only and a color workbook.

Ready for your classroom

25x: Life Sciences - MS - Fifth Edition · 371 pages · Middle School

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